The St. Louis Cardinals make the trip to American Family Field to face the Milwaukee Brewers on Friday, September 25, with first pitch set for 7:40 PM ET. Michael McGreevy gets the ball for St. Louis against Milwaukee's Robert Gasser in what shapes up as a late-season divisional matchup that carries real weight for both clubs. Cardinals fans can catch the action on Cardinals.TV Presented by bet365 or on the radio home of Cardinals baseball, KMOX 1120 AM/104.1 FM.

Cardinals vs. Brewers Pitching Matchup: McGreevy vs. Gasser

Michael McGreevy draws the start for St. Louis in this one. The right-hander has been a part of the Cardinals rotation conversation throughout this season, and Friday night gives him a meaningful late-September stage in a division rivalry setting. How he handles the Brewers lineup at American Family Field will be the central storyline of this game.

Robert Gasser gets the nod for Milwaukee. Gasser is a left-handed arm who the Brewers have leaned on as part of their pitching infrastructure. He's the type of pitcher who can keep a game close when he's commanding his arsenal, so the Cardinals will need to put together disciplined at-bats and avoid chasing early in counts.

Keys to Watch for the Cardinals on Friday Night

  • McGreevy's command against a tough lineup: The Brewers are a disciplined offensive club in their home park. McGreevy will need to establish his fastball early and keep Milwaukee's hitters from working deep counts that drain his pitch count.
  • Cardinals offense against a left-handed starter: Facing Gasser, St. Louis will want to deploy its lineup in a way that pressures him from both sides of the plate. Getting runners on base and making Gasser work will be critical.
  • Bullpen management in a divisional game: Late September divisional games have a way of coming down to the back end of the bullpen. How the Cardinals manage their relief arms — and when they go to them — could define the outcome as much as anything the starters do.
  • Early-inning run support: McGreevy pitches better when he has a lead to work with. Jumping on Gasser in the first couple of innings would go a long way toward keeping the Cardinals in control of this game.

Prediction: Cardinals vs. Brewers, September 25, 2026

This is the kind of game that comes down to pitching execution and timely hitting — two areas where this Cardinals club has shown it can compete. McGreevy has the talent to navigate a tough environment in Milwaukee, but he'll need run support to get the job done. Gasser is a credible challenge, and American Family Field is never an easy place to play in September when the Brewers have something to play for.

Expect a tight, low-scoring game that goes to the later innings. The Cardinals have the pieces to steal one on the road here, but Milwaukee at home in late September is a genuine test. Cardinals 4, Brewers 3.

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