The St. Louis Cardinals wrap up their regular season road schedule with a Friday night trip to American Family Field, where right-hander Michael McGreevy squares off against Milwaukee's Robert Gasser at 7:40 PM ET on September 25. With the NL Central race in its final days, every game in this division rivalry carries real weight. Cardinals fans can catch the action on Cardinals.TV Presented by bet365 or on the radio home of the Redbirds, KMOX 1120 AM/104.1 FM.

Cardinals vs. Brewers Starting Pitchers: McGreevy vs. Gasser

Michael McGreevy gets the ball for St. Louis in what shapes up as a pivotal late-season start. The young right-hander has been part of the Cardinals' rotation conversation throughout 2026, and a strong outing against a Brewers lineup that includes veterans like Christian Yelich and William Contreras would go a long way toward solidifying his value heading into the offseason. Milwaukee counters with Robert Gasser, a left-hander who has carved out his own role in the Brewers' rotation this season. Neither pitcher's current-season numbers are available for this preview, so the matchup reads as genuinely open — whoever commands the strike zone and limits traffic on the bases will have the early advantage.

Cardinals Lineup at Milwaukee: September 25, 2026

• JJ Wetherholt, 2B
• Iván Herrera, DH
• Jordan Walker, RF
• Leo Bernal, 1B
• José Fermín, LF
• Thomas Saggese, 3B
• Masyn Winn, SS
• Pedro Pagés, C
• Victor Scott II, CF

The lineup has a youth-heavy look, which is exactly what you'd expect from a Cardinals organization leaning into its next wave of talent. Jordan Walker batting third puts the spotlight squarely on the 22-year-old outfielder, who has the tools to be the middle-of-the-order presence St. Louis has been building toward. Masyn Winn slots in at shortstop and bats seventh — one of the most electric defensive players in the NL Central, and a guy who can create chaos when he reaches base. JJ Wetherholt leading off is worth watching closely; the rookie second baseman's plate discipline at the top of the order sets the tone for the whole Cardinals offensive approach.

Keys to Watch for St. Louis

• McGreevy's command against a disciplined Brewers lineup: Milwaukee features contact hitters throughout, including Brice Turang and Sal Frelick. McGreevy needs to work ahead in counts and avoid deep counts that can drain his pitch efficiency early.
• Jordan Walker's production in the middle of the order: Batting third, Walker is being asked to carry offensive responsibility. How he handles Gasser's offerings will largely define whether St. Louis can manufacture runs.
• Masyn Winn's defense and baserunning: Even batting seventh, Winn changes the game when he's on the field. Watch for him to impact both sides of the ball.
• Victor Scott II in center field: Batting ninth and playing center, Scott's range and speed give the Cardinals a legitimate defensive asset at the back of the lineup — and a potential spark plug if he can get on base in front of Wetherholt.

Brewers Lineup: September 25, 2026

• Garrett Mitchell, CF
• Brice Turang, 2B
• William Contreras, C
• Jake Bauers, 1B
• Christian Yelich, DH
• Joey Ortiz, SS
• Luis Lara, RF
• Sal Frelick, LF
• David Hamilton, 3B

Yelich hitting fifth as the designated hitter is a legitimate threat McGreevy cannot take lightly. The former MVP has the kind of professional at-bat approach that punishes pitchers who fall behind in counts. William Contreras in the three-hole gives Milwaukee a potent run-producer behind the plate. McGreevy will need to be sharp from the first pitch.

Prediction: Cardinals vs. Brewers, September 25

This is a genuine toss-up on paper. Both pitchers are relatively young and operating without the layer of seasonal statistics that would make a strong lean obvious. The Cardinals' lineup has speed and upside — Winn, Scott, and Wetherholt can make things happen on the bases — but Milwaukee at American Family Field is a tough environment late in the season with a crowd that will be engaged in every at-bat. Give a slight edge to the team that gets the better starting pitching performance, and on Friday night, McGreevy has the chance to be that guy. Cardinals 4, Brewers 3.