The St. Louis Cardinals head to Phoenix for a Saturday afternoon showdown at Chase Field, with first pitch set for 4:10 PM ET on July 18, 2026. Dustin May gets the ball for St. Louis against Arizona's Brandon Pfaadt in what shapes up as a compelling mid-summer pitching duel. For a Cardinals club grinding through the long haul of a 162-game season, every road win in July matters — and this one is no different. Catch the action on KMOX 1120 AM or Cardinals.TV Presented by bet365.
Cardinals vs. Diamondbacks Starting Pitchers: May vs. Pfaadt
Dustin May draws the start for the Cardinals in this one. The right-hander has had a winding road through his major league career, battling injuries and working to establish himself as a reliable rotation arm. When May is on and commanding his sinker-heavy arsenal, he can generate weak contact and keep lineups off-balance. The Cardinals will need him to eat innings and work efficiently against an Arizona lineup that plays in one of the most offense-friendly environments in baseball. Chase Field's retractable roof and altitude can turn routine fly balls into problems for visiting pitchers, so May's ability to stay out of counts where he's forced to elevate will be critical.
Brandon Pfaadt gets the nod for the Diamondbacks. The young right-hander has shown flashes of legitimate front-of-rotation potential since breaking into the big leagues. Pfaadt works with a four-pitch mix and has the ability to miss bats, which makes him a legitimate test for any lineup. The Cardinals will need to work counts early and look for opportunities to get into the Arizona bullpen, particularly if Pfaadt is sharp through the first few frames.
Keys to Watch for the Cardinals at Chase Field
- May's ground-ball rate: Chase Field can punish pitchers who allow fly balls. If May is inducing contact on the ground, he keeps the ballpark out of play. If he's elevated and hittable, Arizona's lineup has the pop to make him pay.
- Cardinals lineup vs. Pfaadt's stuff: Pfaadt has shown the ability to put up strikeouts. St. Louis needs patience at the plate, working deep counts to get a look at his secondary offerings and put pressure on his command early in the game.
- Bullpen management: With the heat of July bearing down and the season at a critical stretch, how both managers deploy their relief corps could be the deciding factor if this game stays close into the seventh inning and beyond.
- Capitalizing on base runners: Road wins are built on situational hitting. The Cardinals need to convert when they get runners into scoring position — a failure to do so against a capable starter like Pfaadt tends to snowball fast.
Prediction: Cardinals vs. Diamondbacks, Saturday July 18
This is a game that hinges on how Dustin May handles the Chase Field environment. If he brings his best sinker command and keeps the ball on the ground, the Cardinals have a legitimate shot to steal a road win. Pfaadt is a real challenge, but a patient Cardinals lineup can chip away. Call it a close, low-scoring affair that comes down to late-inning execution. Cardinals 4, Diamondbacks 3.